Top 50 NGOs Leveraging AI to Drive Social Impact and Address Global Challenges

Spotlighting 50 NGOs using AI to improve response speed by up to 40%, increase resource efficiency by 30–60%, and scale education, health, and climate programs to more communities globally through ethical, data-driven solutions.

Introduction

Artificial intelligence is reshaping how NGOs work. As global problems grow more complex, nonprofits now use AI to boost efficiency, expand reach, and improve results. From disaster relief to conservation, AI helps teams analyze large datasets, spot patterns, and act faster.

Across the sector, leading organizations use AI to fight poverty, strengthen education, improve health, and address climate change. They automate routine tasks, predict needs, and tailor services to local communities. As a result, staff spend less time on manual work and more time delivering impact.

This guide highlights 50 NGOs at the forefront of AI for social good. They use practical, ethical, and scalable tools that deliver measurable outcomes. Together, they show how AI can turn data into timely decisions—and innovative ideas into real-world change.

The Importance of AI in the NGO Sector

AI is doing more than improving how NGOs operate. It is changing how they understand problems and design solutions. By using data and predictive models, NGOs can make faster, more informed decisions and deliver support where it is needed most.

Key ways AI is creating impact:

1. Data-Driven Insights
AI can process large and complex datasets that would otherwise take months to analyze. This gives NGOs clearer visibility into community needs, trends, and risks.

2. Predictive Analytics
Forecasting models help NGOs anticipate crises—such as food shortages, disease outbreaks, or displacement—so they can act before conditions worsen.

3. Personalized Interventions
AI allows organizations to tailor programs to specific groups or individuals. This leads to more targeted, effective, and culturally relevant support.

4. Efficiency and Automation
AI automates repetitive administrative tasks. This gives staff more time to focus on strategic work and direct service delivery.

5. Scalability
Once developed, AI solutions can be expanded to new regions or populations quickly, allowing NGOs to grow their impact faster and at lower cost.

As adoption increases, AI is becoming a core driver of social innovation—helping organizations respond to challenges with greater speed, accuracy, and long-term sustainability.

Criteria for Leading NGOs Using AI

The NGOs making the strongest impact with AI share several key strengths. They focus not only on technology, but on designing solutions that are ethical, scalable, and measurable.

By focusing on these areas, NGOs are not only advancing their missions but also contributing to the broader discourse on ethical and impactful AI use.

50 Top NGOs Leveraging AI for Social Impact in 2025

This list highlights 50 NGOs using artificial intelligence to solve real-world problems in areas such as health, education, climate action, humanitarian response, and economic development. These organizations are applying AI in practical, ethical, and scalable ways to improve decision-making, increase efficiency, and create meaningful change in communities around the world.

While not ranked, this diverse compilation showcases the range of ways in which AI is being harnessed to improve lives and foster sustainable development globally.

1. International Rescue Committee (IRC) 

The International Rescue Committee (IRC), headquartered in New York City, supports people whose lives are disrupted by conflict and disaster. The organization provides healthcare, education, economic recovery support, and protection services to help communities rebuild with dignity and stability.

IRC integrates artificial intelligence to strengthen humanitarian response and improve access to vital information. One example is “aprendIA”, an AI-powered educational chatbot that delivers personalized learning experiences to children in crisis settings where formal schooling is limited. This tool helps maintain learning continuity and improves educational outcomes during emergencies.

Another initiative, “Signpost”, uses AI to deliver accurate, real-time information to displaced populations. Through digital platforms and messaging channels, Signpost connects individuals with essential resources such as legal aid, housing, and medical support. Additionally, IRC is using predictive analytics to anticipate climate-related emergencies. These early-warning systems help identify communities most at risk from floods, enabling faster distribution of cash assistance and more effective preparation efforts.

2. Opportunity International

Opportunity International, based in Chicago, works to break the cycle of poverty by expanding access to financial services, education, and training. The organization focuses especially on empowering women entrepreneurs through microloans, savings programs, and business mentorship. By supporting small business growth, Opportunity International helps families build stable incomes and create stronger local economies.

The organization is integrating artificial intelligence to deepen its impact. In Malawi, Opportunity International launched “UlangiziAI”, a multilingual WhatsApp-based chatbot that provides farmers with real-time agricultural guidance. The chatbot communicates in both English and Chichewa, giving farmers in remote areas access to advice without needing to travel long distances to agricultural centers. During its pilot phase, UlangiziAI answered more than 4,000 queries and received highly positive feedback from farmers for its usefulness and ease of access.

Opportunity International plans to expand this AI solution to Kenya and integrate similar AI tools into its education support programs. These initiatives demonstrate the organization’s commitment to using localized, tech-enabled solutions to promote sustainable development and support communities in improving their livelihoods.

3. Zero Emissions World (ZEW)

Zero Emissions World (ZEW), based in Portugal, is dedicated to addressing climate change by encouraging individuals and organizations to take part in environmental action. The organization builds a global community committed to reducing emissions, supporting sustainability, and participating in planet-positive initiatives. Through its platform, ZEW presents environmental and social projects as engaging “missions” that users can complete, helping turn climate action into a collective and accessible effort.

ZEW incorporates artificial intelligence to refine and personalize user engagement. The platform analyzes participant behavior and motivation to recommend missions that best match individual interests and values. This AI-driven approach helps increase participation, improve donor retention, and ensure that contributions align with meaningful impact goals. By making environmental engagement more relevant and transparent, ZEW strengthens long-term involvement in climate initiatives and fosters a community of active environmental stewards.

4. Animal Ethics

Animal Ethics, based in Portugal, is a nonprofit organization focused on promoting moral consideration and well-being for nonhuman animals. The organization raises awareness about animal suffering, conducts research, and shares practical guidance on how to improve the lives of animals in both human-controlled and natural environments. Their work includes developing interventions to support wild animals during natural hardships, such as disease outbreaks, food scarcity, and environmental disasters.

To expand public understanding and engagement, Animal Ethics has developed “Senti”, an AI-powered educational assistant. Senti provides accessible information on animal ethics, welfare issues, and research-backed strategies for reducing animal suffering. The tool helps make complex ethical topics easier to understand and encourages thoughtful discussion about how society can better protect animals. By combining AI with compassionate outreach, Animal Ethics is working to build a more informed global community that recognizes and supports the rights and needs of all sentient beings.

5. Afri-SET

Afri-SET, based in West Africa, focuses on improving air quality monitoring across the region. The organization evaluates and calibrates low-cost air sensors to ensure communities have access to accurate and reliable pollution data. By increasing transparency around air quality, Afri-SET empowers local governments, researchers, and citizens to make informed environmental and public health decisions.

Afri-SET integrates artificial intelligence to standardize and analyze data from sensors that vary in brand, format, and quality. Their AI-powered smart database processes raw sensor readings, converts them into a unified format, and identifies pollution patterns and hotspots. This system makes it possible to scale air quality monitoring more efficiently across urban and rural areas. By democratizing access to air data, Afri-SET supports stronger advocacy, evidence-based public policy, and community-led environmental action.

6. Data Scientists Network (Nigeria)

Data Scientists Network (formerly Data Science Nigeria), based in Nigeria, is a leading organization focused on building Africa’s capacity in artificial intelligence and data science. Founded in 2016, it aims to train one million AI talents and create solutions that can improve the lives of two billion people in emerging markets. The organization operates through bootcamps, research programs, mentorship networks, and AI clubs in schools and universities to promote accessible and practical AI education.

The organization integrates AI into both learning and social good projects. Its platforms and programs provide training, hands-on project experience, and industry collaboration opportunities. Data Scientists Network also conducts research and publishes resources that help governments, businesses, and nonprofits apply AI to solve economic and development challenges. Through its large community-driven model, the organization is fostering homegrown AI innovation and strengthening the talent pipeline across Africa.

7. PATH

PATH, headquartered in Seattle, Washington, is a global health nonprofit dedicated to advancing health equity. The organization works to strengthen health systems, develop and deliver vaccines and diagnostics, and expand access to essential medicines. PATH partners with governments, research institutions, and private sector organizations to bring health innovations to communities that need them most.

Artificial intelligence plays a growing role in PATH’s work. The organization applies AI to analyze complex health data, support clinical decision-making, and accelerate the development of new medical solutions. PATH has also appointed a Chief AI Officer to ensure that AI is integrated responsibly and strategically across its programs. By using AI to improve diagnostic accuracy, streamline health supply chains, and guide disease surveillance, PATH is helping health systems respond more effectively to public health challenges and improve outcomes for vulnerable populations.

8. Amref Health Africa

Amref Health Africa, headquartered in Nairobi, is the largest Africa-based health organization focused on strengthening health systems and expanding access to care in underserved communities. The organization trains health workers, supports primary healthcare delivery, and addresses critical health issues such as maternal and child health, infectious diseases, HIV, and community sanitation. Its efforts prioritize sustainability by working closely with local governments and communities.

Amref Health Africa integrates artificial intelligence to improve public health outcomes. In partnership with Microsoft’s AI for Good initiative, Amref developed predictive models to identify populations at risk of malnutrition in Kenya. These models help health workers target interventions more effectively, ensuring that resources reach the people who need them the most. By combining AI with community-based healthcare strategies, Amref enhances its ability to deliver timely, data-driven support and strengthen health resilience across the region.

9. Rainforest Connection

Rainforest Connection, based in San Francisco, focuses on protecting rainforests by using advanced acoustic monitoring technology. The organization works with local communities, forest rangers, and conservation groups to detect illegal activities such as logging and poaching in real time. By preserving rainforest ecosystems, Rainforest Connection contributes to biodiversity protection and climate stability.

The organization’s Guardian Platform uses artificial intelligence and machine learning to analyze continuous audio feeds captured by solar-powered listening devices placed high in the forest canopy. These devices, often made from repurposed mobile phones, record ambient sounds and transmit the data to the cloud. The AI system detects chainsaws, vehicle engines, and other unusual human activity, sending instant alerts to on-the-ground teams who can respond quickly. This real-time monitoring approach strengthens conservation efforts, prevents environmental destruction, and helps safeguard endangered species and communities that rely on forest ecosystems.

10. UNICEF

UNICEF, headquartered in New York City, works to protect the rights and well-being of children around the world. The organization focuses on access to healthcare, quality education, safe environments, and equal opportunities for every child, particularly in vulnerable and crisis-affected communities. UNICEF partners with governments, schools, and humanitarian organizations to create long-term, sustainable improvements in children’s lives.

UNICEF is actively integrating artificial intelligence into its programs and policies. The Generation AI initiative ensures that AI tools and systems are designed in ways that uphold and prioritize children’s rights. Through its Venture Fund, UNICEF also supports startups developing AI-powered tools for education, health diagnostics, and learning accessibility. The organization has developed practical guidance for governments and institutions on how to design and deploy child-safe, inclusive AI systems. These efforts demonstrate UNICEF’s commitment to using technology to enhance learning, healthcare access, and protections for children worldwide.

11. One Acre Fund

One Acre Fund, headquartered in Kakamega, Kenya, is a nonprofit organization that supports smallholder farmers across Sub-Saharan Africa. The organization provides farmers with financing, quality seeds, fertilizer, agricultural training, and support services to help increase crop yields and improve household income. One Acre Fund works in multiple countries and supports more than a million farming families each year, focusing on long-term food security and economic resilience.

The organization uses artificial intelligence to strengthen its programs and decision-making processes. AI-driven data models help identify farmers who are at risk of defaulting on seasonal loans, allowing staff to provide additional support and guidance. The organization also applies data analytics to improve service delivery, evaluate program outcomes, and forecast agricultural production trends. By using AI to enhance operational efficiency and deliver targeted assistance, One Acre Fund is helping farming communities improve their productivity, stability, and livelihoods.

12. Digital Green

Digital Green, headquartered in Washington, D.C., is a global development organization focused on improving the livelihoods of small-scale farmers. Working in partnership with governments and local community groups, the organization delivers agricultural training and resources in countries such as India, Ethiopia, and Kenya. Its goal is to help farmers increase productivity, earn higher incomes, and build more resilient farming practices.

Digital Green integrates artificial intelligence into its agricultural extension work. Using AI-powered advisory tools, the organization provides personalized recommendations to farmers based on crop type, location, seasonality, and weather patterns. These tools significantly reduce the cost of delivering agricultural guidance and ensure that farmers receive timely and relevant information. By combining community engagement with scalable AI solutions, Digital Green helps rural farmers adopt better practices, strengthen food security, and improve economic stability.

For building domain-specific assistants like agronomy, health, or education advisors, see how NGOs can implement GenAI agents end-to-end.

13. Ushahidi

Ushahidi, founded in 2008 and headquartered in Nairobi, is a nonprofit technology organization known for developing open-source tools that help communities collect, share, and visualize information. Its platform has been used worldwide for crisis response, election monitoring, human rights reporting, and community engagement. Ushahidi’s mission is to make data more accessible so that citizens and organizations can act together to solve local and global challenges.

Ushahidi is incorporating artificial intelligence to improve how information is gathered and analyzed. By applying AI to categorize, prioritize, and interpret large amounts of incoming data, the organization aims to make its tools easier to use and more effective in fast-changing situations. AI enhancements also support secure and equitable data access, helping communities maintain control over the information they share. Through these efforts, Ushahidi continues to strengthen its role as a leader in civic technology and inclusive data-driven decision-making.

14. Africa’s Voices Foundation (AVF)

Africa’s Voices Foundation (AVF), headquartered in Nairobi and emerging from research at the University of Cambridge, works to amplify citizen voices in decision-making processes across Africa. The organization collaborates with partners such as UNICEF, Oxfam, and the MasterCard Foundation to facilitate participatory discussions around governance, public health, and education. AVF engages communities through radio broadcasts, SMS dialogue, and digital platforms to gather public opinions and ensure that development programs reflect the priorities of the people they aim to serve.

AVF integrates artificial intelligence to analyze large volumes of citizen-generated messages in multiple languages and dialects. Using natural language processing and machine learning, AVF identifies key themes, attitudes, and concerns within public conversations. These insights help inform policy decisions and guide organizations in designing more responsive and contextually appropriate initiatives. By combining AI-driven interpretation with community engagement, AVF strengthens accountability and ensures community voices influence programs intended to support them.

15. Oxfam

Oxfam, headquartered in Nairobi, Kenya, is a global organization dedicated to combating poverty and injustice by addressing the root causes of inequality. Its mission focuses on empowering vulnerable communities, promoting sustainable development, and advocating for human rights. Oxfam operates in numerous countries, implementing programs that provide immediate relief during crises and support long-term development initiatives.

Leveraging artificial intelligence, Oxfam has enhanced its operational efficiency and program effectiveness. By partnering with Ontinue, Oxfam has strengthened its cybersecurity through AI-powered managed extended detection and response (MXDR) services, ensuring the protection of sensitive data and the continuity of its global operations. Additionally, Oxfam’s Innovation Lab explores market-based solutions to development challenges, potentially incorporating AI to analyze data and develop scalable interventions. These AI-driven approaches enable Oxfam to respond more effectively to humanitarian needs and contribute to sustainable development worldwide.

16. Plan International

Plan International, headquartered in Woking, United Kingdom, is a global organization committed to advancing children’s rights and promoting gender equality. Its mission focuses on empowering children, particularly girls, by addressing key issues such as education, health, and protection from violence. Operating in over 75 countries, Plan International works to create lasting positive change in the lives of children and their communities.

Leveraging artificial intelligence, Plan International has integrated AI to enhance its advocacy and operational efficiency. One example is its collaboration with HURIDOCS and Google.org fellows to develop a machine learning-powered human rights database. This tool helps streamline access to crucial data, supporting effective advocacy for girls’ rights on international platforms. Additionally, Plan International Norway partnered with BearingPoint to create an AI-driven application that automates program reporting, reducing manual workload and allowing staff to focus more on impactful program delivery. These AI-driven innovations help Plan International amplify its mission to promote children’s rights and gender equality globally.

17. Care International

CARE International, headquartered in Geneva, Switzerland, is a global humanitarian organization dedicated to combating poverty and social injustice. Their mission focuses on empowering marginalized communities, particularly women and girls, to achieve social and economic equality. In recent years, CARE International has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, CARE International has developed tools to predict and prevent health crises, such as using AI models to forecast and mitigate disease outbreaks. Additionally, CARE International’s Office of Innovation has invested in AI-powered education and health system solutions, supporting startups that utilize AI to improve learning outcomes and healthcare services. Through these initiatives, CARE International aims to harness AI to advance child rights and well-being globally.

18. Doctors Without Borders

Doctors Without Borders (Médecins Sans Frontières, MSF), headquartered in Geneva, Switzerland, is a global humanitarian organization dedicated to providing medical care to populations in crisis. Their mission focuses on delivering emergency medical aid to those affected by conflict, epidemics, disasters, or exclusion from healthcare. In recent years, MSF has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, MSF has developed tools to improve diagnostic accuracy and treatment effectiveness. For instance, they have created a smartphone application, known as ASTapp, which uses image processing and AI technology to assist non-expert microbiologists in interpreting tests that measure antibiotic resistance. This tool aims to guide clinicians in selecting the most appropriate antibiotics, thereby improving patient outcomes.

19. World Wildlife Fund (WWF)

The World Wildlife Fund (WWF), headquartered in Woking, United Kingdom, is a leading global conservation organization committed to protecting the planet’s natural resources and biodiversity. Their mission focuses on conserving the world’s most vulnerable ecosystems and species through science-based initiatives, advocacy, and partnerships. In recent years, WWF has increasingly integrated artificial intelligence (AI) to enhance its conservation efforts.

Leveraging AI, WWF has developed several innovative tools to monitor and protect wildlife and ecosystems. One such initiative is Wildlife Insights, an online platform that uses machine learning to automatically identify and tag animals in camera trap images. This technology enables researchers to process thousands of images within minutes, significantly reducing the time required for data analysis and allowing for more timely conservation interventions.

20. Save the Children

Save the Children, based in London, United Kingdom, is a leading global organization dedicated to improving children’s lives worldwide. Their mission focuses on ensuring that every child has access to healthcare, education, and protection from harm. Save the Children is committed to responding to emergencies and advocating for children’s rights, particularly in areas affected by conflict, disaster, and poverty.

Save the Children is leveraging AI to enhance child protection efforts in Kenya, focusing on addressing critical issues such as child labor, trafficking, and abuse. With Omdena’s collaboration, the organization identified gaps in existing child protection frameworks and developed AI-driven solutions to improve reporting, response services, and resource allocation. Omdena’s expertise in AI facilitated predictive analysis models that informed policy recommendations and tailored interventions, ultimately strengthening the support systems for vulnerable children in Kenya and setting a benchmark for similar global initiatives.

21. World Food Programme (WFP)

The World Food Programme (WFP), headquartered in Rome, Italy, is the leading humanitarian organization addressing global hunger. Their mission focuses on delivering food assistance to those in need, promoting food security, and supporting sustainable development to eradicate hunger worldwide. In recent years, WFP has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, WFP has developed several innovative tools to improve its operations. One such initiative is the UN AI Smart Mission Planner, designed to optimize mission planning and travel resources for humanitarians, thereby accelerating emergency response and enhancing resource utilization across the UN network.  Additionally, WFP’s AI Sandbox serves as a vital resource for assessing the feasibility and potential impact of new AI projects before scaling them up, ensuring that only the most promising and responsible AI solutions are implemented.

22. Habitat for Humanity

Habitat for Humanity, based in Atlanta, Georgia, is a global nonprofit organization dedicated to building affordable housing and promoting homeownership. Their mission focuses on empowering families by providing safe, decent, and affordable homes, fostering community stability and self-reliance. In recent years, the organization has integrated artificial intelligence (AI) to enhance both its operations and fundraising strategies.

Using AI, Habitat for Humanity has optimized fundraising campaigns through tools like Arjuna’s ExactAsk, which analyzes donor data to personalize requests and significantly increase average donation sizes. Additionally, Habitat has partnered with RealPage to leverage AI in housing development, improving operational efficiencies and resource allocation, thereby advancing its mission of building affordable, sustainable communities.

23. Greenpeace

Greenpeace, based in Amsterdam, Netherlands, is an independent global campaigning organization focused on environmental protection and peace. Their mission is to protect biodiversity, reduce pollution, and combat climate change through non-violent methods. Greenpeace aims to secure the Earth’s ability to support life in all its forms by advocating for systemic changes that promote environmental sustainability.

Leveraging artificial intelligence, Greenpeace has explored ways to assess and mitigate environmental impacts, including endorsing the Artificial Intelligence Environmental Impacts Act of 2024 to track AI’s energy consumption and emissions. Additionally, Greenpeace has utilized AI-powered tools like Dataro’s Predict to enhance donor engagement and retention, thereby increasing support for its environmental campaigns and initiatives.

24. The International Committee of the Red Cross (ICRC)

The International Committee of the Red Cross (ICRC), headquartered in Geneva, Switzerland, is a humanitarian organization dedicated to protecting and assisting victims of armed conflict and other situations of violence. Their mission focuses on providing impartial aid, promoting respect for international humanitarian law, and preventing human suffering. In recent years, the ICRC has increasingly integrated artificial intelligence (AI) to enhance its operations and address emerging challenges in conflict zones.

Leveraging AI, the ICRC has developed tools to assess and mitigate the impact of new technologies on humanitarian efforts. They have explored the implications of AI in military decision-making, emphasizing the need for human oversight to prevent unintended consequences. Additionally, the ICRC has engaged in discussions about the ethical use of AI in warfare, advocating for international regulations to ensure that AI applications align with humanitarian principles. Through these initiatives, the ICRC aims to harness AI responsibly, ensuring that technological advancements support and enhance humanitarian action.

25. ActionAid

ActionAid, based in Johannesburg, South Africa, is a global federation focused on eradicating poverty and promoting social justice. Their mission is centered around empowering women and girls, advocating for human rights, and fostering sustainable development through community-driven initiatives. ActionAid strives to address the root causes of poverty and injustice by supporting marginalized communities and advancing social equality.

Leveraging artificial intelligence, ActionAid has integrated AI tools to optimize fundraising and engagement. In collaboration with Dataro, ActionAid Australia used machine learning to target potential donors more effectively, resulting in a significant increase in donations. Additionally, ActionAid Italy developed “Aida,” an AI-powered chatbot that provides real-time information about the organization’s initiatives, making it easier for supporters to interact and stay informed.

26. Mercy Corps

Mercy Corps, based in Portland, Oregon, is a global humanitarian organization focused on alleviating poverty and fostering sustainable development. Their mission is to help communities in crisis build better lives by providing support in areas such as food security, economic development, and climate resilience. Mercy Corps aims to address the root causes of poverty and conflict through innovative and impactful solutions.

Leveraging artificial intelligence, Mercy Corps has implemented AI-driven initiatives like the “AI for Climate Resilience” program, which focuses on improving climate resilience in vulnerable regions through advanced weather forecasting and early warning systems. Additionally, in partnership with Cloudera, they have developed AI tools to optimize humanitarian aid delivery, enabling field teams to make data-driven decisions and improve crisis response efforts.

27. Human Rights Watch

Human Rights Watch, based in New York City, is an international organization focused on investigating and advocating for human rights globally. Their mission is to defend the rights of people worldwide by exposing human rights abuses and pushing governments and other powerful entities to respect human dignity and justice. HRW works to hold perpetrators accountable and ensure justice for victims through rigorous research and advocacy efforts.

Human Rights Watch has engaged with artificial intelligence to assess its potential impact on human rights. The organization has raised concerns about AI technologies perpetuating biases and discrimination, particularly in areas such as hiring practices and surveillance. HRW calls for strong regulatory frameworks to ensure AI development aligns with human rights principles, advocating for policies that prevent AI tools from infringing on civil liberties and disproportionately affecting marginalized communities.

28. WaterAid

WaterAid, based in London, United Kingdom, is an international organization dedicated to improving access to safe water, sanitation, and hygiene in the world’s poorest communities. Their mission is to transform lives by enabling communities to access clean water and sanitation, empowering them to break the cycle of poverty. WaterAid works with local partners to implement sustainable projects that meet the real needs of communities and improve public health.

Leveraging artificial intelligence, WaterAid has integrated AI and automation to enhance its operational efficiency. By using AI to identify potential risks and automate routine tasks, the organization has optimized its internal processes. Additionally, WaterAid has employed AI-enabled models to deliver personalized micro-trainings to staff, which has led to measurable behavior change and increased effectiveness in their mission to provide clean water and sanitation to those in need.

29. Heifer International

Heifer International, based in Little Rock, Arkansas, is a global nonprofit organization dedicated to ending hunger and poverty. Their mission focuses on empowering smallholder farmers through sustainable agricultural solutions, economic development, and environmental stewardship. Heifer works closely with communities to implement programs that improve food security, increase incomes, and enhance resilience to climate change.

Leveraging artificial intelligence, Heifer has collaborated with FruitPunch AI to launch the AI for Women Farmers Challenge. This initiative helps rural women farmers in Nepal use AI tools to digitize business records, access markets, and secure financing. Additionally, Heifer has partnered with IBM to use AI and blockchain technologies in Honduras, assisting coffee and cocoa farmers with supply chain transparency and data-driven decision-making to promote sustainable farming practices.

30. SOS Children’s Villages

SOS Children’s Villages, based in Innsbruck, Austria, is a global nonprofit organization focused on providing family-like care to children who have lost parental care or are at risk of losing it. Their mission centers on creating stable and nurturing environments for children, supporting their overall well-being, and helping them grow into self-reliant adults. The organization operates in over 130 countries, providing family-based care, education, and health services to vulnerable children.

Leveraging artificial intelligence, SOS Children’s Villages has implemented AI-driven tools like Rafiki, a digital care assistant. This chatbot helps caregivers by providing real-time information and support on child protection, mental health, and parenting. Currently available in several African countries, Rafiki is expanding its reach, demonstrating how technology can enhance the organization’s efforts to improve care for children and families in need.

31. GlobalGiving

GlobalGiving, based in Washington, D.C., connects donors with grassroots projects around the world. Their mission is to empower local organizations by providing resources and support to address community needs. Through their platform, GlobalGiving has facilitated millions in donations to thousands of projects, improving lives in over 175 countries.

To enhance their operations, GlobalGiving has incorporated artificial intelligence to improve project assessment, optimize resource allocation, and boost donor engagement. By utilizing AI-driven analytics, the organization can ensure that funds are allocated efficiently, maximizing the impact of their efforts to support local initiatives and foster sustainable development.

32. Feeding America

Feeding America, headquartered in Chicago, Illinois, is the largest hunger-relief organization in the United States. Their mission focuses on ending hunger by providing food to people in need through a network of over 200 food banks and 60,000 food pantries and meal programs across the country. In 2020, Feeding America distributed over 6 billion meals to individuals facing hunger. 

In recent years, Feeding America has increasingly integrated artificial intelligence (AI) to enhance its operations and support its mission. They have utilized AI-driven analytics to optimize food distribution, predict demand, and reduce food waste. By leveraging AI, Feeding America aims to improve efficiency, ensure that food reaches those in need, and contribute to the broader goal of ending hunger in the United States.

33. Ashoka

Ashoka, founded in 1980 by Bill Drayton, is a global nonprofit organization headquartered in Arlington, Virginia. It is the world’s largest network of social entrepreneurs, with over 3,800 Ashoka Fellows in more than 90 countries. These individuals are recognized for their innovative solutions to social problems and their potential for systemic change. Ashoka provides financial support, professional partnerships, and a platform for these changemakers to collaborate and scale their impact. 

In recent years, Ashoka has increasingly integrated artificial intelligence (AI) to enhance its operations and support its mission. The organization has utilized AI-driven analytics to identify emerging social trends, assess the effectiveness of various initiatives, and optimize resource allocation. By leveraging AI, Ashoka aims to improve its ability to support social entrepreneurs and accelerate the adoption of innovative solutions to pressing global challenges.

34. Friends of the Earth

Friends of the Earth, founded in 1969 and based in the United Kingdom, is an international environmental network with member groups in over 70 countries. Their mission is to promote environmental justice, protect biodiversity, and address climate change and pollution. Through grassroots activism and advocacy, they empower communities to take action for a sustainable and just future.

While the organization acknowledges the potential of artificial intelligence (AI) for positive environmental impact, it has also raised concerns about its risks. Friends of the Earth has highlighted the potential for AI to exacerbate climate disinformation and increase energy consumption, contributing to carbon emissions. However, they are exploring how AI can be responsibly used to support their environmental campaigns, ensuring that technology aligns with their mission of protecting the planet.

35. BRAC

BRAC, a leading international development organization based in Bangladesh, is leveraging artificial intelligence (AI) to enhance its development programs, particularly in education and healthcare. The organization has explored AI’s potential in delivering remote learning solutions, especially during the COVID-19 pandemic, by adapting its education delivery through mobile phones, radio, and television broadcasts in countries like Bangladesh, Tanzania, and Uganda. BRAC is also developing machine learning-based systems to improve healthcare, such as a pregnancy risk categorization system aimed at improving maternal health outcomes by targeting resources for women at higher risk of complications.

Additionally, BRAC’s Social Innovation Lab has been hosting dialogues focused on AI’s application in the development sector, discussing how to localize AI solutions to address challenges in the Global South. With a focus on both technological integration and community impact, BRAC continues to demonstrate its commitment to using AI to improve educational access and healthcare services, ensuring the relevance and adaptability of its initiatives to the communities it serves.

36. Kiva

Kiva, a global nonprofit organization dedicated to expanding financial access for underserved communities, has been actively integrating artificial intelligence (AI) to enhance its services. In September 2024, Kiva partnered with OpenAI to develop a Resource Hub aimed at assisting small businesses and social enterprises in leveraging AI tools like ChatGPT for content creation, marketing, and other operational tasks. This collaboration provides easy-to-follow guidance, enabling entrepreneurs to utilize AI effectively, thereby improving efficiency and fostering growth. 

Additionally, Kiva has been involved in AI-related initiatives through Kiva AI, a platform focused on delivering high-quality data labeling, annotation, and reinforcement learning from human feedback (RLHF) solutions. Kiva AI aims to enhance AI model development by providing scalable and cost-effective human feedback, ensuring that AI applications are trained with accurate and contextually relevant data. This approach addresses the critical need for quality human input in AI development, contributing to more effective and reliable AI systems.

37. Malaria Consortium

Malaria Consortium, an international nonprofit focused on combating malaria and other communicable diseases, is utilizing artificial intelligence (AI) to enhance its healthcare initiatives. In 2020, the organization conducted a pilot study using AI on mobile devices to accurately determine respiratory rates in children under five in low-resource settings. This approach aims to improve the diagnosis of pneumonia, a leading cause of child mortality, by making healthcare tools more accessible and efficient in remote areas.

Furthermore, Malaria Consortium is exploring AI applications to strengthen health systems and improve decision-making processes through data. By integrating digital health strategies, including AI, the organization is working to enhance data access and quality, ultimately improving healthcare delivery and outcomes in the communities it serves.

38. Global Citizen

Global Citizen, an international advocacy organization focused on ending extreme poverty, is exploring the role of artificial intelligence (AI) in shaping global governance and promoting social justice. The organization has actively engaged with AI through reports such as “Global Citizen Deliberation on Artificial Intelligence,” which emphasizes the need for citizen involvement in AI governance. The report calls for global deliberations to ensure AI advancements align with societal values and contribute positively to addressing poverty and inequality.

Additionally, Global Citizen is advocating for responsible AI development to protect human rights and freedoms. The organization is exploring the implications of AI on civic space and civil rights, stressing the importance of ethical considerations in AI applications. Through these initiatives, Global Citizen integrates AI discussions into its broader advocacy work, aiming to influence AI governance and ensure that technological progress aligns with its mission of promoting social justice and global equity.

39. UNHCR

The United Nations High Commissioner for Refugees (UNHCR), based in Geneva, Switzerland, is committed to protecting the rights and well-being of refugees and displaced populations worldwide. By providing access to safety, education, healthcare, and livelihood opportunities, UNHCR fosters resilience and empowers communities to rebuild their lives with dignity and hope.

UNHCR leverages AI to enhance its humanitarian impact. In Somalia, “Project Jetson” uses predictive analytics to forecast displacement patterns, enabling proactive resource allocation and crisis management. The organization also applies generative AI to analyze unstructured feedback from refugee communities, identifying emerging trends and needs for data-driven interventions. Furthermore, AI-driven tools support operational efficiency, such as streamlining refugee registration and facilitating faster access to essential services. These innovations allow UNHCR to adapt to evolving challenges and deliver timely, targeted support to vulnerable populations.

40. World Resources Institute

The World Resources Institute (WRI), headquartered in Washington, D.C., is dedicated to advancing environmental sustainability, economic opportunity, and human well-being. Through research and partnerships, WRI tackles critical global issues like climate change, deforestation, and sustainable urban development, ensuring a healthier planet for current and future generations.

WRI integrates AI into its environmental efforts to drive impactful solutions. Its Global Forest Watch platform uses satellite technology and AI to provide near-real-time monitoring of forests, helping prevent deforestation and support conservation strategies. Additionally, WRI’s Data Lab applies AI to analyze complex datasets, offering insights that guide sustainable development initiatives and climate resilience strategies worldwide.

41. International Medical Corps

International Medical Corps, based in Los Angeles, California, is a global humanitarian organization that provides healthcare and emergency relief to communities affected by conflict, disaster, and disease. Their mission focuses on strengthening local healthcare systems and training healthcare workers to provide sustainable medical services, while also addressing the root causes of health disparities in vulnerable regions.

The organization integrates artificial intelligence (AI) to enhance its response and operational capabilities. Using IBM’s analytics platform, International Medical Corps accelerates reporting and decision-making, which allows for quicker deployment of medical resources and responders during emergencies. Additionally, AI-driven tools are employed to streamline healthcare data collection and analysis, enabling better-targeted interventions and more efficient healthcare delivery in crisis situations.

42. The Nature Conservancy

The Nature Conservancy (TNC), based in Arlington, Virginia, is dedicated to conserving the lands and waters on which all life depends. Through their global efforts, TNC focuses on protecting nature for its intrinsic value and its critical role in supporting human life, ensuring clean air, water, and sustainable ecosystems for future generations.

TNC integrates artificial intelligence (AI) to advance its conservation initiatives. In Palmyra Atoll, AI-powered image analysis helped identify two additional seabird species, enhancing habitat restoration efforts. TNC also collaborates with Microsoft to leverage AI for addressing key environmental challenges, such as improving coastal resilience, floodplain management, and watershed protection. Furthermore, AI tools are used to analyze complex natural systems, supporting more sustainable energy planning for hydropower and river protection.

43. Grameen Foundation 

Grameen Foundation, established in 1997 by Alex Counts, is a global nonprofit organization headquartered in Washington, D.C. Inspired by the work of Nobel Laureate Muhammad Yunus, the foundation’s mission is to enable the poor, especially women, to create a world without poverty and hunger. Operating across Asia, Africa, and the Americas, Grameen Foundation empowers marginalized populations through innovative solutions to address the multifaceted challenges of poverty.

In recent years, Grameen Foundation has integrated artificial intelligence (AI) to enhance financial inclusion and decision-making among low-income populations. Collaborating with Accenture Labs, they developed AI-driven applications like Emotional Analytics for Social Enterprises (EASE) and Grameen Guru, which provide real-time insights and financial literacy support. These AI initiatives aim to improve the adoption of financial services, particularly in regions like India, thus promoting financial empowerment globally.

44. Environmental Defense Fund 

Environmental Defense Fund (EDF), established in 1967, is a global nonprofit organization headquartered in New York City. EDF is dedicated to building a vital Earth for everyone, focusing on stabilizing the climate, ensuring sustainable fisheries, and protecting public health through science-based solutions and partnerships.

In recent years, EDF has increasingly integrated artificial intelligence (AI) into its initiatives to enhance environmental protection efforts. Notably, EDF has used AI-driven analytics for hyperlocal air quality mapping in cities like Oakland and London, providing precise data to target pollution hotspots. Additionally, the Smart Boat Initiative uses AI and sensor technologies to transform fishing practices, promoting sustainability. Through these AI applications, EDF aims to develop innovative, data-driven solutions to complex environmental challenges, furthering its mission to create a sustainable future.

45. ACLU

The American Civil Liberties Union (ACLU), founded in 1920, is a nonprofit organization headquartered in New York City. Its mission is to defend and preserve the individual rights and liberties guaranteed to every person in the United States by the Constitution and laws. The ACLU operates nationwide, focusing on areas like free speech, privacy, and equality through litigation, advocacy, and public education.

In recent years, the ACLU has addressed the impact of artificial intelligence (AI) on civil liberties, particularly in perpetuating systemic biases in employment, housing, and credit. The organization advocates for equitable AI systems, challenging discriminatory practices, and policies. It also monitors AI use in national security and law enforcement, warning against potential risks to privacy and freedom. Through these efforts, the ACLU ensures that AI advancements align with constitutional rights and civil liberties.

46. Amnesty International

Amnesty International, founded in 1961 by Peter Benenson, is a global human rights organization headquartered in London, United Kingdom. Its mission is to conduct research and take action to prevent and end grave abuses of human rights worldwide. Operating in over 150 countries, Amnesty International addresses issues such as freedom of expression, abolition of the death penalty, and the rights of refugees and migrants.

Amnesty International has been actively addressing the human rights implications of artificial intelligence (AI) and related technologies. The organization has raised concerns about AI’s role in mass surveillance, discrimination, and the erosion of privacy rights. For example, it has criticized AI-powered welfare systems that may lead to surveillance and discrimination against marginalized groups. Additionally, Amnesty has highlighted the use of AI at borders, emphasizing how such technologies can increase inequalities and undermine the human rights of migrants. Through research and advocacy, Amnesty International seeks to ensure that AI technologies are developed and deployed in ways that respect and uphold human rights globally.

47. Room to Read

Room to Read, founded in 2000 and headquartered in San Francisco, California, is a nonprofit organization dedicated to eliminating illiteracy and gender inequality. Its mission focuses on improving literacy and supporting girls’ education across more than 24 countries. The organization collaborates with local communities to develop essential literacy skills and empower girls to succeed in school and beyond.

While Room to Read has not yet publicly integrated artificial intelligence (AI) into its programs, it continues to explore innovative solutions to enhance education. With a focus on educational access and quality, AI could potentially play a significant role in providing personalized learning experiences, improving literacy tools, and expanding access to resources, all of which could support Room to Read’s mission of transforming education for children globally.

48. GAIN 

The Global Alliance for Improved Nutrition (GAIN), established in 2002 and headquartered in Geneva, Switzerland, is a nonprofit organization dedicated to combating malnutrition worldwide. Its mission is to advance nutrition outcomes by improving the consumption of nutritious and safe food for all people, especially the most vulnerable to malnutrition. Operating in over 25 countries, GAIN collaborates with governments, businesses, and civil society to design and implement food-based policies and programs that encourage the consumption of nutritious and safe foods. 

GAIN has recognized the potential of artificial intelligence (AI) to enhance nutrition programming. The organization has issued a request for proposals to develop AI recommendations aimed at strengthening nutrition initiatives. This initiative seeks to leverage AI technologies to improve the effectiveness and reach of nutrition interventions, aligning with GAIN’s commitment to innovative solutions in the fight against malnutrition. 

49. Operation Smile

Operation Smile, established in 1982 and headquartered in Virginia Beach, Virginia, is a nonprofit organization dedicated to providing free reconstructive facial surgeries to children and adults worldwide who suffer from cleft lips and palates. Their mission is to improve the health and lives of these individuals by offering comprehensive care, including surgeries, dental care, speech therapy, and psychological support. Operating in over 35 countries, Operation Smile has performed more than 400,000 surgeries, transforming the lives of countless patients and their families.

In collaboration with Microsoft, Operation Smile has integrated artificial intelligence (AI) into their operations to enhance patient care and surgical outcomes. By leveraging AI, the organization analyzes pre- and post-surgical photographs to objectively assess the severity of cleft conditions and evaluate surgical results. This integration allows for consistent, measurable evaluations, ensuring high-quality care even in regions with limited access to specialized cleft surgeons. The AI program also aids in educating surgeons in remote areas, bringing the expertise of experienced professionals to underserved communities.

50. mySociety

mySociety, founded in 2003 and headquartered in the United Kingdom, is a nonprofit organization dedicated to empowering citizens through digital technology, research, and data. Its mission is to enhance civic participation by providing tools that enable individuals to engage more effectively with democratic processes. mySociety operates services such as TheyWorkForYou, WhatDoTheyKnow, WriteToThem, and FixMyStreet, which facilitate access to governmental information and promote community involvement. 

In recent years, mySociety has been exploring the integration of artificial intelligence (AI) into its platforms to better serve its mission. The organization has developed an AI framework to guide the ethical and effective use of AI technologies in enhancing civic engagement. This framework addresses considerations for deploying generative AI and machine learning within mySociety’s services, ensuring that technological advancements align with their commitment to responsible and impactful civic tech solutions. 

NGOs and AI: Pioneering Social Impact and Global Change

At the forefront of tackling the world’s most pressing challenges, NGOs are harnessing AI to reshape how social issues are addressed. By embracing cutting-edge technologies and focusing on data-driven, scalable solutions, these organizations are not only enhancing their impact but also driving innovation in the non-profit sector.

Through AI-powered analytics, predictive models, and automated systems, these NGOs are setting new standards by achieving key objectives:

• Enhancing Efficiency: Streamlining operations to allocate resources more effectively and reach more people in need.
• Driving Innovation: Utilizing AI to develop new methods for solving complex global issues like poverty, health crises, and climate change.
• Personalizing Interventions: Tailoring programs to better meet the unique needs of different communities, ensuring more targeted and effective outcomes.

At Omdena, we collaborate with leading NGOs to leverage AI for social good, helping them scale their efforts and maximize their impact. Join us in driving a future where technology empowers organizations to create sustainable, meaningful change.